Formulation and Evaluation of Floating Tablets of Cefpodoxime Proxetil
نویسندگان
چکیده
منابع مشابه
Cefpodoxime Proxetil Floating Microspheres: Formulation and In Vitro Evaluation
The objective of the present study was to develop floating microspheres of cefpodoxime proxetil in order to achieve an extended retention in the upper GIT, which may result in enhanced absorption and thereby improved bioavailability. The microspheres were prepared by non-aqueous solvent evaporation method using polymers such as hydroxyl propyl methyl cellulose (HPMC K 15 M), ethyl cellulo...
متن کاملcefpodoxime proxetil floating microspheres: formulation and in vitro evaluation
the objective of the present study was to develop floating microspheres of cefpodoxime proxetil in order to achieve an extended retention in the upper git, which may result in enhanced absorption and thereby improved bioavailability. the microspheres were prepared by non-aqueous solvent evaporation method using polymers such as hydroxyl propyl methyl cellulose (hpmc k 15 m), ethyl cellulose in ...
متن کاملSimultaneous spectrophotometric determination of cefpodoxime proxetil and ofloxacin in tablets
The present manuscript describe simple, sensitive, rapid, accurate, precise and economical Q-absorbance ratio method for the simultaneous determination of cefpodoxime proxetil and ofloxacin in combined tablet dosage form. Absorbance ratio method uses the ratio of absorbances at two selected wavelengths, one which is an isoabsorptive point and other being the λ-max of one of the two components. ...
متن کاملFormulation and in vitro characterization of cefpodoxime proxetil gastroretentive microballoons
BACKGROUND AND THE PURPOSE OF THE STUDY The objective of the present work was to improve bioavailability of cepodoxime proxetil through gastroretentive microballoon formulation. METHODS Microballoons of cefpodoxime proxetil were formulated by solvent evaporation and diffusion method employing hydroxypropylmethyl cellulose (HPMC) and ethyl cellulose (EC) polymers and characterized for particle...
متن کاملPreparation and evaluation of solid dispersions of cefpodoxime proxetil
Solid dispersions (SDs) are one of the most promising strategies to improve the oral bioavailability of poorly water soluble drugs. This technology is mainly applied to improve the solubility of Class II and Class IV drugs. Cefpodoxime proxetil (CP) is chosen as drug as it belongs to Class IV i. e. having low solubility and low permeability (Solubility: 400 μg/ml). SDs were prepared by using PV...
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ژورنال
عنوان ژورنال: Journal of Scientific Research
سال: 2014
ISSN: 2070-0245,2070-0237
DOI: 10.3329/jsr.v6i3.18339